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27800 Medical Center Road, Suite 244
Mission Viejo, CA 92691
675 Camino de Los Mares, Suite 403
San Clemente, CA 92673
15785 Laguna Canyon Road, Suite 100
Irvine, 92618
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Research Studies

Our Research Division (Southern California Research) has been participating in FDA regulated research studies for almost 30 years. In fact, most medications currently available for either allergy conditions or asthma were at one point studied in our center.

Our research center is dedicated to the research, development and progress of new therapies for a number of different disorders that will improve the quality of life for patients. We are continually enrolling patients of all ages in research studies. At this time we are conducting trials for adult and pediatric patients with allergies, asthma, or chronic hives. We may have a study that is right for you!

For more information about research, review our current studies below, find answers to common questions about research or fill out an online interest form and we will follow up with you. You can also call us at 949-347-8700 ext. 1800.


Current Studies

Below is a list on some of our current studies with basic qualification details. Click on each study for more information. If you don't see one that fits your needs, give us a call at 949-347-8700 ext. 1800. We are opening new studies regularly.

• Air Pollution Exposure Survey for Asthmatic and Healthy Children (0-18 years old): Participants need to have documented asthma but no other lung disease OR no asthma, no nasal allergies, and no respiratory / lung disease. The child’s mother or guardian will be asked to complete seven (7) separate questionnaires about the overall health and environment of the child. Estimated time is 30 minutes or more depending on personal situation. Study coordinator is available for any help in accessing or completing questionnaires. You may also click on Screening Questionnaireabove to begin the process and see if you qualify. Coordinator can be reached at ext. 1906.

    • Chronic Hives / Urticaria: Participants 12 and older with chronic hives

    • Adult Asthma: Participants need to be willing to wean down to rescue inhalers only

    Adult Asthma: Participants need to have had 2 asthma exacerbations in the last year that required the use of oral steroids

    Adult Asthma: Participants need to currently be taking combination ICS and LABA therapy

    • Adult Asthma: Participants need to currently be using high dose Advair or Symbicort

    • Adolescent and Adult Asthma: Participants need to be diagnosed with allergic asthma and need to have had at least 1 asthma exacerbation in the last 12 months that required the use of oral steroids

    • Adolsecent and Adult Asthma: Patients must be taking ICS or combination therapy (ICS and LABA). This trial includes 3 different studies to study patients at different dosing levels.

    • Adolscent and Adult Excercise Induced Asthma: Patients need to be on daily asthma medication AND require the use of a rescue inhaler before, during or after most exercise. The study will require patients to exercise in the clinic.

    Pediatric Asthma: Participants need to be using an inhaled corticosteroid

    Pediatric Asthma: Participants need to be taking ICS with our without LABA therapy


    Common Questions About Research

    What is a clinical trial?

    A clinical trial is a research study designed to study the effectiveness and use of a drug or medical device in a select group of patients with a specific condition. These drugs or devices that are being tested have been extensively studied in laboratories and through animal research before they are ever tested on people.

    Once a drug or medical device enters the clinical trial phase, it must go through three phases of testing on specific patient groups before the drug or device can be approved for more wide-spread use. Research studies are important because they help the medical community improve and develop new treatments for improved quality of life for patients.


    What does someone do in a research study?

    Each research study is designed differently, according to the product that is being studied and the outcomes the study is looking to achieve. Some studies involve only a few office visits, while other studies can involve several office visits. During those office visits, the research participant is asked a number of questions about how they are feeling. The participant may also have an EKG, complete some breathing tests, or give a blood sample.

    Often, research participants are required to keep a diary of how they are feeling during the study. The diaries are provided by the research study and ask specific questions.

    When a person is deciding to participate in a research study, they will meet with a research coordinator who will inform them exactly how many visits are involved and what is required during participation.


    Why would I want to participate in a clinical trial?

    There are a number of reasons to participate:

    • The treatment being tested may improve your health

    • You are helping others with conditions just like yours by allowing your condition to be studied

    • Only through clinical trials can new therapies become available on the market

    • Study medications, procedures and doctor visits are provided by the sponsor of the study, at no cost to you


    What about work and school?

    We offer extended hours to meet your busy schedule. If you are interested in participating in a trial, please let us know how we can work with you.



    Who pays for the clinical trials?

    Most of our clinical trials are paid for by the company sponsoring the trial. This means the care and medications provided are at no expense to you or your insurance company. In the event that your insurance company would need to be billed you would be notified before you make a decision to participate in the trial.


    What about the time I spend for the trial?

    If you participate in a research study, you receive compensation for the time and travel involved with your participation. Since each study requires a different amount of participation, the compensation varies with the study. When you meet with one of our coordinators, everything will be explained to you regarding study requirements and compensation.


    I am interested in learning more, what next?

    Complete our online interest form or call us at 949-347-8700 ext. 1800.